Wedged between the Mzikaba and Mtentu Rivers, Mkambati is the Wild Coast’s largest nature reserve. Apart from conserving a 13-kilometre  long strip of grassland and unspoilt, rocky coastline, the reserve is known for its endemic plants such as the Mkambati palm, which is found only on the north banks of the rivers. Cape vultures breed in the Mzikaba Gorge. The Mkambati River flows through the reserve in a series of waterfalls of which Horseshoe Falls, near the sea, is the most striking.

Accommodations ranges from a stone lodge to cottages. Outdoor activities include swimming, fishing, and horse riding. Animals include eland, springbok, blesbok, impala, blue wildebeest and zebra. An added attraction is that the reser4ve is near the Wild Coast Sun Hotel and Casino.