Opened in 1915, the Santa Fe railway depot was built to commemorate the completion of the Panama Canal in 1914 and Dan Diego’s ensuing celebration of it. The distinctive Spanish Colonial-style train station was designed by San Francisco architects Jon Bakewell and Arthur Brown, Jr. it continues to serve Amtrak riders, tour buses bound for Mexico, and Coaster and trolley commuter traffic.

The depot’s crowning glory also happens to be its most striking exterior detail: Rising form a red tile roof are twin towers capped by blue and yellow glazed tiles, laid in a zigzag pattern and bearing the Santa Fe Railroad’s distinctive cross-inside-a-circle emblem.